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For instance, certain NOX members, such as NOX4, are overexpressed in various types of cancer (e.g., hepatocellular carcinoma and renal cell carcinoma) [19, 20]

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The variant allele 718C of the GPX4 gene was found to be significantly associated with an increased risk of CS in hypertensive patients (odds ratio (OR) 1.53, 95% confidence interval (CI) 1.231.90, P adj =0.0003)

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